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Endocrine Abstracts

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ea0056oc11.1 | Clinical practice in endocrine tumours: combining conventional and molecular features | ECE2018

Targeted molecular analysis in adrenocortical carcinomas: a way towards improved personalized prognostication

Lippert Juliane , Appenzeller Silke , Liang Raimunde , Sbiera Silviu , Kircher Stefan , Altieri Barbara , Nanda Indrajit , Weigand Isabel , Gehrig Andrea , Steinhauer Sonja , Mueller Clemens , Kroiss Matthias , Rost Simone , Rosenwald Andreas , Fassnacht Martin , Ronchi Cristina

Adrenocortical carcinoma (ACC) has heterogeneous prognosis and no effective targeted therapies. Pan-genomic studies identified complex molecular patterns related to outcome. Our study aimed at identification of an ‘easy-to-apply’ molecular signature for better personalized prognostic stratification. A total of 107 ACC patients were enrolled. Clinical/histopathological parameters of prognostic relevance were evaluated. Targeted molecular analysis was performed on DNA ...
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Published by BioScientifica

Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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